Schematic diagram show the process of DBS. In DBS, STN or thalamus or the globus pallidus interna (Gpi) (in this case STN) are stimulated by an implanted apparatus contains batteries that produce electrical stimulation (like a pace-maker). Stimulating the STN can activate the GPi, which can strongly inhibit the thalamus (right side circuitry) which can activate the motor cortex; in turn, allowing more control into the movement of limbs
Let The Right One In Epub 28
In Vitro Effects of Lead on Gene Expression in Neural Stem Cells and Associations between Up-regulated Genes and Cognitive Scores in Children. Wagner PJ, Park HR, Wang Z, Kirchner R, Wei Y, Su L, Stanfield K, Guilarte TR, Wright RO, Christiani DC, Lu Q. Environ Health Perspect. 2017 Apr;125(4):721-729. doi: 10.1289/EHP265. Epub 2016 Aug 26.
Dysregulation of BDNF-TrkB signaling in developing hippocampal neurons by Pb(2+): implications for an environmental basis of neurodevelopmental disorders. Stansfield KH, Pilsner JR, Lu Q, Wright RO, Guilarte TR. Toxicol Sci. 2012 May;127(1):277-95. doi: 10.1093/toxsci/kfs090. Epub 2012 Feb 17.
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padding: 5rem; margin: auto 0 1.5rem 0; /*padding: 35px 35px; margin-bottom: 35px; text-align: center;*/.blue-well p, .blue-well ol, .blue-well ul, .blue-well li, .blue-well a, .blue-well a:hover, .blue-well a:active color: #ffffff !important; font-size: 1.75rem !important; /*line-height: normal !important;*/ letter-spacing: normal; font-weight: 500; list-style: inherit;.blue-well-nav-bar padding: 2rem;.blue-well h3, .blue-well h4 color: #ffffff !important; font-size: 2.25rem !important; letter-spacing: normal; font-weight: auto;.blue-well-large-text font-size: 2rem !important; font-weight: 700;.blue-well ol, .blue-well ul padding-left: 2rem;.blue-well a, .blue-well a:hover, .blue-well a:active border-bottom: dotted 0.1rem #ffffff;.blue-well a:hover border-bottom: none;.blue-well-header color: #ffffff !important; line-height: normal !important;.vertical-line-left border-left: solid #eeeeee 5px; font-size: 1.2em; padding: 1em 1em; margin-bottom: 1.2em !important;.vertical-line-right border-right: 1px solid rgba(51,51,51,.2); font-size: 1.2em; padding: 1em 1em; margin-bottom: 1.2em !important;.horizontal-line-top-drk border-top: solid #aaa 1px; padding: 1rem 0 1rem 0; margin: 4rem 0 auto 0; max-width: 70%;.horizontal-line-top border-top: solid #eeeeee 5px; padding: 1rem 0 1rem 0; margin: 4rem 0 auto 0; max-width: 70%;.horizontal-line-top-blue-arrow border-top: solid #eeeeee 5px; background: url( ) no-repeat; margin-top: 20px; min-height: 30px; padding-left: 40px; max-width: 60%;.top-bottom-dashed-line margin: 3rem auto; padding: 3rem 3rem; border-top: 2px dashed #aaa; border-bottom: 2px dashed #aaa; width: 95%;/* ***** padding and text copy-specific styles ***** */.top-padding margin-top: 2rem;.photo-credit font-size: 14px !important; margin-bottom: 2rem; .caps text-transform: uppercase; .text-tagline font-size: 2rem !important; font-weight: 700;.text-blue color: #337ab7;.text-lead-lg font-size: 18px !important;/* **** icons for links ***** */a.icon-blue-book::after font-family: 'FontAwesome'; content:'\f2b9'; color:#009edb; padding: 0 1px 0 5px;a.social-icon-android::after font-family: 'FontAwesome'; content:'\f17b'; color:#009edb; padding: 0 1px 0 5px;a.social-icon-apple::after font-family: 'FontAwesome'; content:'\f179'; color:#009edb; padding: 0 1px 0 5px;/* ***** lists ul/ol ***** */ul.underline-links li a, ol.underline-links li a border-bottom: dotted 0.1rem #333333ul.underline-links li a:hover, ol.underline-links li a:hover border-bottom: none;ol.ol-decimal list-style-type: decimal;ol.ol-lower-latin list-style-type: lower-latin;ol.ol-decimal, ol.ol-lower-latin margin: 1rem 1.5rem; padding: 0.5rem 1rem 1.75rem 1rem;ol.ol-decimal li, ol.ol-lower-latin li margin: 1.5rem 0; padding-left: 2rem;ul.block-list li font-weight: 700; border-bottom: #eeeeee dotted 2px;ul.spaced-list li padding: 1.5rem 0;ul.block-list li a:before font-family: FontAwesome; display: inline-block; padding-right: 6px; vertical-align: middle; content: "\f105"; font-size: 32.24px; font-weight: 600; color: #009edb; margin-right: 0.3em;ul.block-list li h4 a:before display: none;/*ul.block-list li.leaf:before font-family: FontAwesome; display: inline-block; padding-right: 6px; vertical-align: middle; content: "\f105"; font-size: 32.24px; font-weight: 600; color: #009edb; margin-right: 0.3em;*/ul.block-list li a font-size: 2rem; font-weight: 600;/* ************* side bar nav menu **************** */.node-sidebar-item-body .menu > li > a padding: 10px 0px; /* font-weight: bold; */.node-sidebar-item-body ul list-style: none;.node-sidebar-item-body ul li margin: 10px 0px;.node-sidebar-item-body ul li a:hover text-decoration: underline;.node-sidebar-item-body p a:hover border-bottom: none;.menu-sub padding-left: 2em; list-style: circle !important;/* ********* some padding for side bar items ********** */.node-sidebar-item-body margin-top: 1em; /************ some interactivity */.eventitem -webkit-box-shadow: 0 1px 3px rgba(0, 0, 0, 0.12), 0 1px 2px rgba(0, 0, 0, 0.24); -moz-box-shadow: 0 1px 3px rgba(0, 0, 0, 0.12), 0 1px 2px rgba(0, 0, 0, 0.24); -ms-box-shadow: 0 1px 3px rgba(0, 0, 0, 0.12), 0 1px 2px rgba(0, 0, 0, 0.24); -o-box-shadow: 0 1px 3px rgba(0, 0, 0, 0.12), 0 1px 2px rgba(0, 0, 0, 0.24); box-shadow: 0 1px 3px rgba(0, 0, 0, 0.12), 0 1px 2px rgba(0, 0, 0, 0.24); -webkit-transition: all 0.25s ease-in-out; -moz-transition: all 0.25s ease-in-out; -ms-transition: all 0.25s ease-in-out; -o-transition: all 0.25s ease-in-out; transition: all 0.25s ease-in-out;.eventitem:hover -webkit-box-shadow: 0 10px 20px rgba(0, 0, 0, 0.19), 0 6px 6px rgba(0, 0, 0, 0.23); -moz-box-shadow: 0 10px 20px rgba(0, 0, 0, 0.19), 0 6px 6px rgba(0, 0, 0, 0.23); -ms-box-shadow: 0 10px 20px rgba(0, 0, 0, 0.19), 0 6px 6px rgba(0, 0, 0, 0.23); -o-box-shadow: 0 10px 20px rgba(0, 0, 0, 0.19), 0 6px 6px rgba(0, 0, 0, 0.23); box-shadow: 0 10px 20px rgba(0, 0, 0, 0.19), 0 6px 6px rgba(0, 0, 0, 0.23); opacity: 0.7;/* ******* phone ********** */@media (max-width: 400px) {.grey-well padding: 1rem; margin: auto 0 1.5rem 0; background-color: #f5f5f5; border: 1px solid #e3e3e3; border-radius: 0px; -webkit-box-shadow: inset 0 1px 1px rgba(0,0,0,0.05); box-shadow: inset 0 1px 1px rgba(0,0,0,0.05); /* -- end added by Tulin -- *//* -- begin added by Gedi --*/.back-button margin-top: 1em;.card-body a border-bottom: dotted 0.1rem #333333;.back-to-toplink text-align: right; padding-top: 5px; font-size: 1.2em;.back-to-toplink a border-bottom: dotted 0.1rem #333333;.flag-container float: right !important;.country box-shadow: 5px 5px 3px #f2f2f2; padding: 10px; margin-bottom: 10px;#memberStatesIndex border: solid 1px #000; background: #eee; padding: 10px; text-align: center; margin-bottom: 1em;#memberStatesIndex a padding: 9px; font-size: 1.25em; font-weight: 700;.member-state-grouping-letter text-align: center; font-size: 2em !important; font-weight: bold; margin: 1em 0 0.5em 0;.member-state-grouping-letter a border: none;.onimage_title display: none;.main-container.container margin-top: 2rem; margin-bottom: 3em;.image-metadata border:none; margin-bottom: 0px; padding-bottom: 0px;.carousel-caption.top-text bottom: 30px; padding: 10px; background: rgba(77,77,77,0.9); border-radius: 10px; left: 5%; right: 5%;.carousel-caption.top-text p text-align: left; color:#ffffff;.carousel-caption.top-text button background-color: #009edb;.section1 margin-top: 15px!important; margin-bottom: 25px !important;h2.international-selection text-align: center;.observances background: #009EDB; padding: 15px 0;.observance-item background: #4d4d4d;.observance-item-title padding:5px 10px !important; font-size: 2.5rem !important;.observance-item-title a color:#ffffff !important;.observance-item-title a:hover text-decoration: underline !important;.international-items padding: 20px; box-shadow: 5px 5px 3px #f2f2f2; position: relative; .international-items.resolution bottom: 20px; right: 20px; text-align: right; /* **** adjusting for screen size ***** */@media only screen and (min-width: 1200px) .carousel-caption.top-text /*top: 100px;*/ bottom: 100px; padding: 20px; border-radius: 10px; width: 360px; left: 5%; right: 60%; .carousel-caption.top-text p color:#ffffff; width: 310px; margin: auto 0; @media only screen and (min-width: 992px) .un-anniversaries text-align: right; .un-multilingualism text-align: left; .unorg-home-hero.col-md-3 width: 25% !important; @media only screen and (min-width: 992px) .international-items height: 205px; .international-items.resolution position: absolute; /* ******************** end added by Gedi ***************** */ 2ff7e9595c
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